Human RAC2 activation kit by CRISPRa

CAT#: GA103994

RAC2 CRISPRa kit - CRISPR gene activation of human Rac family small GTPase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAC2
• Locus ID: 5880
• Kit Components:

  GA103994G1, RAC2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA103994G2, RAC2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA103994G3, RAC2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002872, NM_014029
• Synonyms: EN-7; Gx; HSPC022; p21-Rac2
• Summary: This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]