Human hHR23A (RAD23A) activation kit by CRISPRa

CAT#: GA103999

RAD23A CRISPRa kit - CRISPR gene activation of human RAD23 homolog A, nucleotide excision repair protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAD23A
• Locus ID: 5886
• Kit Components:

  GA103999G1, hHR23A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103999G2, hHR23A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103999G3, hHR23A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270362, NM_001270363, NM_005053, NR_072976
• Synonyms: HHR23A; HR23A
• Summary: 'The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair. Proteins in this family have a modular domain structure consisting of an ubiquitin-like domain (UbL), ubiquitin-associated domain 1 (UbA1), XPC-binding domain and UbA2. The protein encoded by this gene plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012]'