Human RAP1B activation kit by CRISPRa

CAT#: GA104018

RAP1B CRISPRa kit - CRISPR gene activation of human RAP1B, member of RAS oncogene family

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAP1B
• Locus ID: 5908
• Kit Components:

  GA104018G1, RAP1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104018G2, RAP1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104018G3, RAP1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001010942, NM_001251917, NM_001251918, NM_001251921, NM_001251922, NM_015646
• Synonyms: K-REV; RAL1B
• Summary: 'This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011]'