Human PLAAT4 activation kit by CRISPRa

CAT#: GA104030

PLAAT4 CRISPRa kit - CRISPR gene activation of human phospholipase A and acyltransferase 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLAAT4
• Locus ID: 5920
• Kit Components:

  GA104030G1, PLAAT4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104030G2, PLAAT4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104030G3, PLAAT4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004585
• Synonyms: HRASLS4; HRSL4; PLA1/2-3; RIG1; TIG3
• Summary: 'Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008]'