Human RASGRF2 activation kit by CRISPRa

CAT#: GA104034

RASGRF2 CRISPRa kit - CRISPR gene activation of human Ras protein specific guanine nucleotide releasing factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RASGRF2
• Locus ID: 5924
• Kit Components:

  GA104034G1, RASGRF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104034G2, RASGRF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104034G3, RASGRF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006909
• Synonyms: GRF2; RAS-GRF2
• Summary: 'RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]'