Human KDM5A activation kit by CRISPRa

CAT#: GA104037

KDM5A CRISPRa kit - CRISPR gene activation of human lysine demethylase 5A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KDM5A
• Locus ID: 5927
• Kit Components:

  GA104037G1, KDM5A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104037G2, KDM5A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104037G3, KDM5A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042603, NM_005056
• Synonyms: RBBP-2; RBBP2; RBP2
• Summary: 'This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013]'