Human Radixin (RDX) activation kit by CRISPRa

CAT#: GA104061

RDX CRISPRa kit - CRISPR gene activation of human radixin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RDX
• Locus ID: 5962
• Kit Components:

  GA104061G1, Radixin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104061G2, Radixin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104061G3, Radixin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001260492, NM_001260493, NM_001260494, NM_001260495, NM_001260496, NM_002906, N92548
• Synonyms: DFNB24
• Summary: 'Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]'