Human REG1 alpha (REG1A) activation kit by CRISPRa

CAT#: GA104064

REG1A CRISPRa kit - CRISPR gene activation of human regenerating family member 1 alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: REG1A
• Locus ID: 5967
• Kit Components:

  GA104064G1, REG1 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104064G2, REG1 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104064G3, REG1 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002909
• Synonyms: ICRF; P19; PSP; PSPS; PSPS1; PTP; REG
• Summary: 'This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]'