Human Rhodopsin (RHO) activation kit by CRISPRa

CAT#: GA104103

RHO CRISPRa kit - CRISPR gene activation of human rhodopsin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RHO
• Locus ID: 6010
• Kit Components:

  GA104103G1, Rhodopsin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104103G2, Rhodopsin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104103G3, Rhodopsin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000539
• Synonyms: CSNBAD1; OPN2; RP4
• Summary: 'The protein encoded by this gene is found in rod cells in the back of the eye and is essential for vision in low-light conditions. The encoded protein binds to 11-cis retinal and is activated when light hits the retinal molecule. Defects in this gene are a cause of congenital stationary night blindness. [provided by RefSeq, Aug 2017]'