Human GRK1 activation kit by CRISPRa

CAT#: GA104104

GRK1 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor kinase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GRK1
• Locus ID: 6011
• Kit Components:

  GA104104G1, GRK1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA104104G2, GRK1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA104104G3, GRK1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002929
• Synonyms: GPRK1; RHOK; RK
• Summary: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008]