Human RNF2 activation kit by CRISPRa

CAT#: GA104118

RNF2 CRISPRa kit - CRISPR gene activation of human ring finger protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RNF2
• Locus ID: 6045
• Kit Components:

  GA104118G1, RNF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104118G2, RNF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104118G3, RNF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007212
• Synonyms: BAP-1; BAP1; DING; HIPI3; RING1B; RING2
• Summary: 'Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq, Jul 2008]'