Human RPL13 activation kit by CRISPRa

CAT#: GA104155

RPL13 CRISPRa kit - CRISPR gene activation of human ribosomal protein L13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RPL13
• Locus ID: 6137
• Kit Components:

  GA104155G1, RPL13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104155G2, RPL13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104155G3, RPL13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000977, NM_001243130, NM_001243131, NM_033251
• Synonyms: BBC1; D16S44E; D16S444E; L13
• Summary: 'Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L13E family of ribosomal proteins. It is located in the cytoplasm. This gene is expressed at significantly higher levels in benign breast lesions than in breast carcinomas. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2011]'