Human RPL15 activation kit by CRISPRa

CAT#: GA104156

RPL15 CRISPRa kit - CRISPR gene activation of human ribosomal protein L15

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RPL15
• Locus ID: 6138
• Kit Components:

  GA104156G1, RPL15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104156G2, RPL15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104156G3, RPL15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001253379, NM_001253380, NM_001253382, NM_001253383, NM_001253384, NM_002948
• Synonyms: DBA12; EC45; L15; RPL10; RPLY10; RPYL10
• Summary: 'Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L15E family of ribosomal proteins and a component of the 60S subunit. This gene shares sequence similarity with the yeast ribosomal protein YL10 gene. Elevated expression of this gene has been observed in esophageal tumors and gastric cancer tissues, and deletion of this gene has been observed in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Mar 2017]'