Human RPL27 activation kit by CRISPRa

CAT#: GA104167

RPL27 CRISPRa kit - CRISPR gene activation of human ribosomal protein L27

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RPL27
• Locus ID: 6155
• Kit Components:

  GA104167G1, RPL27 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104167G2, RPL27 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104167G3, RPL27 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000988, NM_001349921, NM_001349922, NR_146327
• Synonyms: L27
• Summary: 'Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L27e family of ribosomal proteins and a component of the 60S subunit. A splice site mutation in this gene has been identified in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Mar 2017]'