Human RPL34 activation kit by CRISPRa

CAT#: GA104174

RPL34 CRISPRa kit - CRISPR gene activation of human ribosomal protein L34

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RPL34
• Locus ID: 6164
• Kit Components:

  GA104174G1, RPL34 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104174G2, RPL34 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104174G3, RPL34 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000995, NM_001319232, NM_001319234, NM_001319235, NM_001319236, NM_033625
• Synonyms: L34
• Summary: 'Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Overexpression of this gene has been observed in some cancer cells. Alternative splicing results in multiple transcript variants, all encoding the same isoform. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Feb 2016]'