Human Ribophorin II (RPN2) activation kit by CRISPRa

CAT#: GA104189

RPN2 CRISPRa kit - CRISPR gene activation of human ribophorin II

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RPN2
• Locus ID: 6185
• Kit Components:

  GA104189G1, Ribophorin II gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104189G2, Ribophorin II gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104189G3, Ribophorin II gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135771, NM_002951, NM_001324299, NM_001324301, NM_001324302, NM_001324303, NM_001324304, NM_001324305, NM_001324306
• Synonyms: RIBIIR; RPN-II; RPNII; SWP1
• Summary: 'This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]'