Human RPS17 activation kit by CRISPRa

CAT#: GA104213

RPS17 CRISPRa kit - CRISPR gene activation of human ribosomal protein S17

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RPS17
• Locus ID: 6218
• Kit Components:

  GA104213G1, RPS17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104213G2, RPS17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104213G3, RPS17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001021, NR_111943, NR_111944
• Synonyms: DBA4; RPS17L; RPS17L1; RPS17L2; S17
• Summary: 'Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17E family of ribosomal proteins and is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia 4. Alternative splicing of this gene results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Apr 2014]'