Human RRM1 activation kit by CRISPRa

CAT#: GA104230

RRM1 CRISPRa kit - CRISPR gene activation of human ribonucleotide reductase catalytic subunit M1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RRM1
• Locus ID: 6240
• Kit Components:

  GA104230G1, RRM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA104230G2, RRM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA104230G3, RRM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033, NM_001318064, NM_001318065, NM_001330193
• Synonyms: R1; RIR1; RR1
• Summary: This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]