Human RRM2 activation kit by CRISPRa

CAT#: GA104231

RRM2 CRISPRa kit - CRISPR gene activation of human ribonucleotide reductase regulatory subunit M2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RRM2
• Locus ID: 6241
• Kit Components:

  GA104231G1, RRM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104231G2, RRM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104231G3, RRM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001034, NM_001165931
• Synonyms: R2; RR2; RR2M
• Summary: 'This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009]'