Human Reticulon 1 (RTN1) activation kit by CRISPRa

CAT#: GA104237

RTN1 CRISPRa kit - CRISPR gene activation of human reticulon 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RTN1
• Locus ID: 6252
• Kit Components:

  GA104237G1, Reticulon 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104237G2, Reticulon 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104237G3, Reticulon 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021136, NM_206852, NM_206857, NM_001243115, NM_001363702
• Synonyms: NSP
• Summary: 'This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]'