Human S100A4 activation kit by CRISPRa

CAT#: GA104253

S100A4 CRISPRa kit - CRISPR gene activation of human S100 calcium binding protein A4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: S100A4
• Locus ID: 6275
• Kit Components:

  GA104253G1, S100A4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104253G2, S100A4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104253G3, S100A4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002961, NM_019554
• Synonyms: 18A2; 42A; CAPL; FSP1; MTS1; P9KA; PEL98
• Summary: 'The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]'