Human S100 Calcium Binding Protein A13 (S100A13) activation kit by CRISPRa

CAT#: GA104262

S100A13 CRISPRa kit - CRISPR gene activation of human S100 calcium binding protein A13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: S100A13
• Locus ID: 6284
• Kit Components:

  GA104262G1, S100 Calcium Binding Protein A13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104262G2, S100 Calcium Binding Protein A13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104262G3, S100 Calcium Binding Protein A13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024210, NM_001024211, NM_001024212, NM_001024213, NM_005979
• Synonyms: OTTHUMP00000034802; S100 calcium-binding protein A13; S100 calcium binding protein A13
• Summary: 'The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]'