Human SAT1 activation kit by CRISPRa

CAT#: GA104277

SAT1 CRISPRa kit - CRISPR gene activation of human spermidine/spermine N1-acetyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SAT1
• Locus ID: 6303
• Kit Components:

  GA104277G1, SAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104277G2, SAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104277G3, SAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002970, NR_027783
• Synonyms: DC21; KFSD; KFSDX; SAT; SSAT; SSAT-1
• Summary: 'The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]'