Human SBF1 activation kit by CRISPRa

CAT#: GA104279

SBF1 CRISPRa kit - CRISPR gene activation of human SET binding factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SBF1
• Locus ID: 6305
• Kit Components:

  GA104279G1, SBF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104279G2, SBF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104279G3, SBF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002972, NM_001365819
• Synonyms: CMT4B3; DENND7A; MTMR5
• Summary: 'This gene encodes a member of the protein-tyrosine phosphatase family. However, the encoded protein does not appear to be a catalytically active phosphatase because it lacks several amino acids in the catalytic pocket. This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation. Mutations in this gene have been associated with Charcot-Marie-Tooth disease 4B3. Pseudogenes of this gene have been defined on chromosomes 1 and 8. [provided by RefSeq, Dec 2014]'