Human SCN3A activation kit by CRISPRa

CAT#: GA104294

SCN3A CRISPRa kit - CRISPR gene activation of human sodium voltage-gated channel alpha subunit 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SCN3A
• Locus ID: 6328
• Kit Components:

  GA104294G1, SCN3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104294G2, SCN3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104294G3, SCN3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001081676, NM_001081677, NM_006922
• Synonyms: NAC3; Nav1.3
• Summary: 'Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'