Human Nav1.7 (SCN9A) activation kit by CRISPRa

CAT#: GA104300

SCN9A CRISPRa kit - CRISPR gene activation of human sodium voltage-gated channel alpha subunit 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SCN9A
• Locus ID: 6335
• Kit Components:

  GA104300G1, Nav1.7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104300G2, Nav1.7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104300G3, Nav1.7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002977, NM_001365536
• Synonyms: ETHA; FEB3B; GEFSP7; HSAN2D; Nav1.7; NE-NA; NENA; PN1; SFNP
• Summary: 'This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009]'