Human Macrophage Inflammatory Protein 3 beta (CCL19) activation kit by CRISPRa

CAT#: GA104326

CCL19 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 19

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCL19
• Locus ID: 6363
• Kit Components:

  GA104326G1, Macrophage Inflammatory Protein 3 beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104326G2, Macrophage Inflammatory Protein 3 beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104326G3, Macrophage Inflammatory Protein 3 beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006274
• Synonyms: CKb11; ELC; MIP-3b; MIP3B; SCYA19
• Summary: 'This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]'