Human Eotaxin 2 (CCL24) activation kit by CRISPRa

CAT#: GA104331

CCL24 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 24

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCL24
• Locus ID: 6369
• Kit Components:

  GA104331G1, Eotaxin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104331G2, Eotaxin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104331G3, Eotaxin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002991
• Synonyms: Ckb-6; MPIF-2; MPIF2; SCYA24
• Summary: 'This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. Finally, the protein is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2020]'