Human SEL1L activation kit by CRISPRa

CAT#: GA104353

SEL1L CRISPRa kit - CRISPR gene activation of human SEL1L adaptor subunit of ERAD E3 ubiquitin ligase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEL1L
• Locus ID: 6400
• Kit Components:

  GA104353G1, SEL1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104353G2, SEL1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104353G3, SEL1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001244984, NM_005065
• Synonyms: PRO1063; SEL1-LIKE; SEL1L1
• Summary: 'The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]'