Human CD62P (SELP) activation kit by CRISPRa

CAT#: GA104356

SELP CRISPRa kit - CRISPR gene activation of human selectin P

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SELP
• Locus ID: 6403
• Kit Components:

  GA104356G1, CD62P gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104356G2, CD62P gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104356G3, CD62P gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003005
• Synonyms: CD62; CD62P; GMP140; GRMP; LECAM3; PADGEM; PSEL
• Summary: 'This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]'