Human SFRP5 activation kit by CRISPRa

CAT#: GA104370

SFRP5 CRISPRa kit - CRISPR gene activation of human secreted frizzled related protein 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SFRP5
• Locus ID: 6425
• Kit Components:

  GA104370G1, SFRP5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104370G2, SFRP5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104370G3, SFRP5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003015
• Synonyms: SARP3
• Summary: 'Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. [provided by RefSeq, Jul 2008]'