Human SF2 (SRSF1) activation kit by CRISPRa

CAT#: GA104371

SRSF1 CRISPRa kit - CRISPR gene activation of human serine and arginine rich splicing factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SRSF1
• Locus ID: 6426
• Kit Components:

  GA104371G1, SF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104371G2, SF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104371G3, SF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001078166, NM_006924, NR_034041
• Synonyms: ASF; SF2; SF2p33; SFRS1; SRp30a
• Summary: 'This gene encodes a member of the arginine/serine-rich splicing factor protein family. The encoded protein can either activate or repress splicing, depending on its phosphorylation state and its interaction partners. Multiple transcript variants have been found for this gene. There is a pseudogene of this gene on chromosome 13. [provided by RefSeq, Jun 2014]'