Human alpha Sarcoglycan (SGCA) activation kit by CRISPRa

CAT#: GA104383

SGCA CRISPRa kit - CRISPR gene activation of human sarcoglycan alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SGCA
• Locus ID: 6442
• Kit Components:

  GA104383G1, alpha Sarcoglycan gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104383G2, alpha Sarcoglycan gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104383G3, alpha Sarcoglycan gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000023, NM_001135697, NR_135553
• Synonyms: 50-DAG; A2; adhalin; ADL; DAG2; DMDA2; LGMD2D; SCARMD1
• Summary: 'This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]'