Human delta Sarcoglycan (SGCD) activation kit by CRISPRa

CAT#: GA104385

SGCD CRISPRa kit - CRISPR gene activation of human sarcoglycan delta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SGCD
• Locus ID: 6444
• Kit Components:

  GA104385G1, delta Sarcoglycan gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104385G2, delta Sarcoglycan gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104385G3, delta Sarcoglycan gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000337, NM_001128209, NM_172244
• Synonyms: 35DAG; CMD1L; DAGD; SG-delta; SGCDP; SGD
• Summary: 'The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]'