Human SHMT1 activation kit by CRISPRa
CAT#: GA104403
SHMT1 CRISPRa kit - CRISPR gene activation of human serine hydroxymethyltransferase 1
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | SHMT1 |
Locus ID | 6470 |
Kit Components | GA104403G1, SHMT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104403G2, SHMT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104403G3, SHMT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001281786, NM_004169, NM_148918 |
Synonyms | CSHMT; SHMT |
Summary | 'This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]' |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN403461 | SHMT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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