Human SI activation kit by CRISPRa

CAT#: GA104407

SI CRISPRa kit - CRISPR gene activation of human sucrase-isomaltase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SI
• Locus ID: 6476
• Kit Components:

  GA104407G1, SI gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104407G2, SI gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104407G3, SI gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001041
• Synonyms: MGC131621; MGC131622
• Summary: 'This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010]'