Human ST3GAL3 activation kit by CRISPRa

CAT#: GA104414

ST3GAL3 CRISPRa kit - CRISPR gene activation of human ST3 beta-galactoside alpha-2,3-sialyltransferase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ST3GAL3
• Locus ID: 6487
• Kit Components:

  GA104414G1, ST3GAL3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104414G2, ST3GAL3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104414G3, ST3GAL3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270459, NM_001270460, NM_001270461, NM_001270462, NM_001270463, NM_001270464, NM_001270465, NM_001270466, NM_006279, NM_174963, NM_174964, NM_174965, NM_174966, NM_174967, NM_174968, NM_174969, NM_174970, NM_174971, NM_174972, NR_073016, NR_073017, NR_073018, NR_073019, NR_073020, NR_073021, NR_073023, NM_001350619, NM_001350620, NM_001350621, NR_146867, NM_001363573
• Synonyms: EIEE15; MRT12; SIAT6; ST3GALII; ST3GalIII; ST3N
• Summary: 'The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with a form of autosomal recessive nonsymdromic cognitive disability as well as infantile epileptic encephalopathy. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]'