ST3GAL3 Human Gene Knockout Kit (CRISPR)

CAT#: KN408261

ST3GAL3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

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Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: ST3GAL3
• Locus ID: 6487
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001270459, NM_001270460, NM_001270461, NM_001270462, NM_001270463, NM_001270464, NM_001270465, NM_001270466, NM_006279, NM_174963, NM_174964, NM_174965, NM_174966, NM_174967, NM_174968, NM_174969, NM_174970, NM_174971, NM_174972, NR_073016, NR_073017, NR_073018, NR_073019, NR_073020, NR_073021, NR_073023, NM_001350619, NM_001350620, NM_001350621, NR_146867, NM_001363573
• Synonyms: EIEE15; MRT12; SIAT6; ST3GALII; ST3GalIII; ST3N
• Summary: 'The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with a form of autosomal recessive nonsymdromic cognitive disability as well as infantile epileptic encephalopathy. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]'