Human GLUT4 (SLC2A4) activation kit by CRISPRa

CAT#: GA104441

SLC2A4 CRISPRa kit - CRISPR gene activation of human solute carrier family 2 member 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC2A4
• Locus ID: 6517
• Kit Components:

  GA104441G1, GLUT4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104441G2, GLUT4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104441G3, GLUT4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042
• Synonyms: GLUT4
• Summary: 'This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]'