Human SGLT2 (SLC5A2) activation kit by CRISPRa

CAT#: GA104448

SLC5A2 CRISPRa kit - CRISPR gene activation of human solute carrier family 5 member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC5A2
• Locus ID: 6524
• Kit Components:

  GA104448G1, SLC5A2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA104448G2, SLC5A2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA104448G3, SLC5A2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003041, NR_130783
• Synonyms: SGLT2
• Summary: This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015]