Human SLC8A3 activation kit by CRISPRa

CAT#: GA104469

SLC8A3 CRISPRa kit - CRISPR gene activation of human solute carrier family 8 member A3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC8A3
• Locus ID: 6547
• Kit Components:

  GA104469G1, SLC8A3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA104469G2, SLC8A3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA104469G3, SLC8A3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130417, NM_033262, NM_058240, NM_182932, NM_182933, NM_182936, NM_183002, NR_104122
• Synonyms: NCX3
• Summary: This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Aug 2013]