Human SLC16A2 activation kit by CRISPRa

CAT#: GA104486

SLC16A2 CRISPRa kit - CRISPR gene activation of human solute carrier family 16 member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC16A2
• Locus ID: 6567
• Kit Components:

  GA104486G1, SLC16A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104486G2, SLC16A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104486G3, SLC16A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006517
• Synonyms: AHDS; DXS128; DXS128E; MCT 7; MCT7; MCT 8; MCT8; MRX22; XPCT
• Summary: 'This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012]'