Human Citrate transport protein (SLC25A1) activation kit by CRISPRa

CAT#: GA104495

SLC25A1 CRISPRa kit - CRISPR gene activation of human solute carrier family 25 member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC25A1
• Locus ID: 6576
• Kit Components:

  GA104495G1, Citrate transport protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104495G2, Citrate transport protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104495G3, Citrate transport protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256534, NM_001287387, NM_005984, NR_033687, NR_046298
• Synonyms: CTP; D2L2AD; SEA; SLC20A3
• Summary: 'This gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate small metabolites across the mitochondrial membrane. This protein regulates the movement of citrate across the inner membranes of the mitochondria. Mutations in this gene have been associated with combined D-2- and L-2-hydroxyglutaric aciduria. Pseudogenes of this gene have been identified on chromosomes 7, 11, 16, and 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]'