Human SLC22A2 activation kit by CRISPRa

CAT#: GA104500

SLC22A2 CRISPRa kit - CRISPR gene activation of human solute carrier family 22 member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC22A2
• Locus ID: 6582
• Kit Components:

  GA104500G1, SLC22A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104500G2, SLC22A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104500G3, SLC22A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003058, NM_153191
• Synonyms: OCT2
• Summary: 'Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. [provided by RefSeq, Jul 2008]'