Human SLN activation kit by CRISPRa

CAT#: GA104505

SLN CRISPRa kit - CRISPR gene activation of human sarcolipin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLN
• Locus ID: 6588
• Kit Components:

  GA104505G1, SLN gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104505G2, SLN gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104505G3, SLN gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003063
• Synonyms: MGC12301; MGC125854; MGC125855
• Summary: 'Sarcoplasmic reticulum Ca(2+)-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of Ca(2+) from the cytosol into the lumen of the sarcoplasmic reticulum in muscle cells. This gene encodes a small proteolipid that regulates several sarcoplasmic reticulum Ca(2+)-ATPases. The transmembrane protein interacts with Ca(2+)-ATPases and reduces the accumulation of Ca(2+) in the sarcoplasmic reticulum without affecting the rate of ATP hydrolysis. [provided by RefSeq, Jul 2008]'