Human SLPI activation kit by CRISPRa

CAT#: GA104506

SLPI CRISPRa kit - CRISPR gene activation of human secretory leukocyte peptidase inhibitor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLPI
• Locus ID: 6590
• Kit Components:

  GA104506G1, SLPI gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104506G2, SLPI gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104506G3, SLPI gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003064
• Synonyms: ALK1; ALP; BLPI; HUSI; HUSI-I; MPI; WAP4; WFDC4
• Summary: 'This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity. [provided by RefSeq, Nov 2014]'