Human HLTF activation kit by CRISPRa

CAT#: GA104510

HLTF CRISPRa kit - CRISPR gene activation of human helicase like transcription factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HLTF
• Locus ID: 6596
• Kit Components:

  GA104510G1, HLTF gRNA vector 1 in pCas-Guide-CRISPRa

  GA104510G2, HLTF gRNA vector 2 in pCas-Guide-CRISPRa

  GA104510G3, HLTF gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318934, NM_003071, NM_139048, NM_001318935
• Synonyms: HIP116; HIP116A; HLTF1; RNF80; SMARCA3; SNF2L3; ZBU1
• Summary: This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 2008]