Human SMRC2 (SMARCC2) activation kit by CRISPRa

CAT#: GA104514

SMARCC2 CRISPRa kit - CRISPR gene activation of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SMARCC2
• Locus ID: 6601
• Kit Components:

  GA104514G1, SMRC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104514G2, SMRC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104514G3, SMRC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130420, NM_001330288, NM_003075, NM_139067
• Synonyms: BAF170; CRACC2; Rsc8
• Summary: 'The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'