Human Sumo 3 (SUMO3) activation kit by CRISPRa

CAT#: GA104525

SUMO3 CRISPRa kit - CRISPR gene activation of human small ubiquitin like modifier 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SUMO3
• Locus ID: 6612
• Kit Components:

  GA104525G1, Sumo 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104525G2, Sumo 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104525G3, Sumo 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286416, NM_006936
• Synonyms: SMT3A; Smt3B; SMT3H1; SUMO-3
• Summary: 'This gene encodes a member of the small ubiquitin-related modifier (SUMO) family of eukaryotic proteins. The encoded protein is covalently conjugated to other proteins via a post-translation modification known as sumoylation. Sumoylation may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, mitosis, transcriptional regulation, and signal transduction. Alternatively spliced transcript variants encoding distinct proteins have been described. [provided by RefSeq, Feb 2014]'