Human SNRPB activation kit by CRISPRa

CAT#: GA104541

SNRPB CRISPRa kit - CRISPR gene activation of human small nuclear ribonucleoprotein polypeptides B and B1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SNRPB
• Locus ID: 6628
• Kit Components:

  GA104541G1, SNRPB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104541G2, SNRPB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104541G3, SNRPB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003091, NM_198216
• Synonyms: CCMS; COD; Sm-B/B; SmB/B; SmB/SmB; snRNP-B; SNRPB1
• Summary: 'The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]'